Detox Nalgene

What's New

Drinking from polycarbonate Nalgene water bottles is an everyday activity for millions of people who want to stay healthy and hydrated while reducing their impact on the planet. Unfortunately, Nalgene users are getting an unhealthy dose of bisphenol-A, the known endocrine disruptor, which leaches from polycarbonate water bottles into liquids. Studies indicate bisphenol A may lead to serious health problems including miscarriage, chromosomal defects and prostate cancer.

How You Can Help

Environment Massachusetts is working with the Detox Nalgene campaign and calling on Nalgene to switch from using the chemical bisphenol A in their polycarbonate water bottles to a safer alternative. To get involved, visit www.detoxnalgene.com.

Resources

Bisphenol-A Fact sheet 

Links to studies on bisphenol-A and other endocrine disruptors:

Cancer Research 66, 5624-5632, June 1, 2006
Developmental Exposure to Estradiol and Bisphenol-A Increases Susceptibility to Prostate Carcinogenesis and Epigenetically Regulates Phosphodiesterase Type 4 Variant 4

Shuk-Mei Ho, Wan-Yee Tang, Jessica Belmonte de Frausto and Gail S. Prins

Environmental Health Perspectives Volume 111, Number 9, July 2003
Bisphenol-A Is Released from Used Polycarbonate Animal Cages into Water at Room Temperature

Kembra L. Howdeshell, Paul H. Peterman, Barbara M. Judy, Julia A. Taylor, Carl E. Orazio, Rachel L. Ruhlen, Frederick S. vom Saal, and Wade V. Welshons

Environmental Health Perspectives Volume 109, Number 1, January 2001
High Incidence of a Male-Specific Genetic Marker in Phenotypic Female Chinook Salmon from the Columbia River

James J. Nagler, Jerry Bouma, Gary H. Thorgaard, and Dennis D. Dauble

Environmental Research Volume 100, Issue 1, January 2006, Pages 50-76.
Large effects from small exposures. II. The importance of positive controls in low-dose research on bisphenol-A.

Frederick S. vom Saal and Wade V. Welshons

Environmental Research Volume 100, Issue 1, January 2006, Pages 39-43.
Increased serum estrogenic bioactivity in three male newborns with ambiguous genitalia: A potential consequence of prenatal exposure to environmental endocrine disruptors

Françoise Paris, Claire Jeandel, Nadège Servant and Charles Sultan

Environmental Health Perspectives Volume 114, Number 1, January 2006
The Estrogenic Effect of BisphenolA Disrupts Pancreatic β-Cell Function In Vivo and Induces Insulin Resistance.

Paloma Alonso-Magdalena, Sumiko Morimoto,Cristina Ripoll, Esther Fuentes, and Angel Nadal

Human Reproduction
Exposure to bisphenol-A is associated with recurrent miscarriage.

Mayumi Sugiura-Ogasawara, Yasuhiko Ozaki, Shin-ichi Sonta, Tsunehisa Makino, and Kaoru Suzumori

Endocrinology 146: 4138-4147
Perinatal Exposure to Bisphenol-A Alters Peripubertal Mammary Gland Development in Mice

Monica Muñoz-de-Toro, Caroline M. Markey, Perinaaz R. Wadia, Enrique H. Luque, Beverly S. Rubin, Carlos Sonnenschein and Ana M. Soto

Environmental Health Perspectives Volume 113, Number 4, April 2005
Urinary Concentrations of Bisphenol-A and 4-Nonylphenol in a Human Reference Population

Antonia M. Calafat, Zsuzsanna Kuklenyik, John A. Reidy, Samuel P. Caudill, John Ekong, and Larry L. Needham